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Primary Rhesus Immunization of Male Volunteers
Author(s) -
Cook I. A.
Publication year - 1971
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1971.tb07048.x
Subject(s) - immunization , medicine , antibody , titer , immunology
S ummary . To provide high titre plasma for the preparation of anti‐D immunoglobulin, three groups of group A Rh negative (cde/cde) male volunteers, totalling 34 men, were immunized with Group A Rh positive (cDE/cde) blood. Twenty‐three men (68%) developed Rhesus antibodies. The importance of adequate safeguards in the planning of such immunization schemes, as well as continued medical supervision, is stressed.