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Prognosis in Hodgkin's Disease Related to the Lymphocyte Count
Author(s) -
Swan H. T.,
Knowelden J.
Publication year - 1971
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1971.tb03446.x
Subject(s) - lymphocyte , medicine , chemotherapy , disease , radiation therapy , peripheral blood lymphocyte , immunology , oncology
S ummary . Case notes of 328 histologically‐diagnosed patients with Hodgkin's disease have been studied in respect to sex, age of presentation, lymphocyte count in the peripheral blood and survival. Lymphocyte counts were accepted only if they had been made before the first course of radiotherapy or cytotoxic chemotherapy. A clear difference in prognosis has been demonstrated in three lymphocyte groups. The worst prognosis was associated with lymphocyte counts of less than 1000/μl in which group the proportion of patients surviving 5 yr was only 12%. The prognosis was better where the initial counts were between 1000 and 1500/μl, the 5‐yr survival being 26%, and was best where the lymphocyte counts were above 1500/μl, the 5‐yr survival being 35%.