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The Eosinophil Leucocytes in the Blood and Bone Marrow of Patients with Down's Anomaly
Author(s) -
Archer R. K.,
Engisch H. J. C.,
Gaha T.,
Ruxton J.
Publication year - 1971
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1971.tb03439.x
Subject(s) - eosinophil , promyelocyte , bone marrow , medicine , anomaly (physics) , pathology , eosinophilic , immunology , asthma , physics , condensed matter physics
S ummary . A study has been made of blood and bone‐marrow films obtained from mentally subnormal patients with Down's anomaly and without this anomaly. It was found that the eosinophils in all stages of maturation subsequent to the promyelocyte were about half as frequent in the mongol patients as in the controls. An investigation of the nuclear lobulation of eosinophils in these patients showed that there were at least twice as many with three or four lobes in mongol patients than in control patients; this finding is in contrast with that well established for the neutrophil leucocytes in mongolism.