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The Measurement of Reticuloendothelial Iron Release using Iron—Dextran
Author(s) -
Beamish M. R.,
Davies A. G.,
Eakins J. D.,
Jacobs A.,
Trevett D.
Publication year - 1971
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1971.tb02725.x
Subject(s) - mononuclear phagocyte system , transferrin , dextran , erythropoiesis , rheumatoid arthritis , medicine , immunology , chemistry , anemia , biochemistry
S ummary An index of reticuloendothelial cell release of iron for erythropoiesis can be derived from simultaneous measurements of iron—dextran and transferrin‐bound iron utilization. Reticuloendothelial iron release was found to be reduced in patients with Hodgkins disease, chronic renal failure and some cases of rheumatoid arthritis. It was increased in patients with iron deficiency.