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Electrophoretic Patterns of Red‐Cell Membrane Protein from Various Mammalian Species
Author(s) -
Gomperts E. D.,
Cantrell A. C.,
Zail S. S.
Publication year - 1971
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1971.tb02703.x
Subject(s) - electrophoresis , membrane , polyacrylamide gel electrophoresis , biology , red cell , starch , microbiology and biotechnology , chemistry , biochemistry , chromatography , enzyme , computer security , computer science
S ummary . Electrophoresis of solubilized red‐cell membrane protein was carried out on eight mammalian species. Haemoglobin‐free membranes were extracted with n‐butanol to obtain the material for study. Four electrophoretic systems were used, viz.: starch gel at pH 3.2 and 8.6 and polyacrylamide disc and flat gels at pH 3.2. All four systems showed similarities as well as differences in the electrophoretic patterns of the species studied. The human and monkey samples showed a similar overall pattern as did those of the bovine, sheep and pig. The results obtained support the hypothesis that certain structural and functional properties common to all membranes owe their similarity to specific common protein components.