Premium
A Comparative Study of Hypersplenism in Reactive and Congestive Splenomegaly
Author(s) -
Bagshawe A.
Publication year - 1970
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1970.tb07018.x
Subject(s) - medicine , portal hypertension , visceral leishmaniasis , spleen , gastroenterology , splenectomy , hemodynamics , pathology , leishmaniasis , cirrhosis
S ummary . Anaemia, leucopenia, and thrombocytopenia due to hypersplenism have been compared in 75 patients. Forty‐six patients had congestive splenomegaly due to portal hypertension. Twenty‐nine patients had reactive splenomegaly due in 27 to idiopathic tropical splenomegaly, and in two to visceral leishmaniasis. The only definite difference between the two groups was a lesser degree of lymphopenia in patients with reactive splenomegaly. It is suggested that this difference may be explained by an increase in production of lymphocytes in idiopathic tropical splenomegaly and that manifestations of hypersplenism are not directly influenced by histological or haemodynamic differences within the enlarged spleen.