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Thrombokinetics in Idiopathic Thrombocytopenic Purpura *
Author(s) -
Harker Laurence A.
Publication year - 1970
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1970.tb01605.x
Subject(s) - thrombopoiesis , megakaryocytopoiesis , platelet , thrombocytopenic purpura , medicine , immunology , megakaryocyte , haematopoiesis , biology , microbiology and biotechnology , stem cell
S ummary Measurements of platelet production in 16 patients with idiopathic thrombocytopenic purpura (ITP) demonstrate that megakaryocytopoiesis (total thrombopoiesis) and platelet turnover (effective thrombopoiesis) are increased in parallel to as much as 8 times normal. The marrow megakaryocytes show changes characteristic of stimulated thrombopoiesis.
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