Premium
The Incidence of Glucose‐6‐Phosphate Dehydrogenase Deficiency and Thalassaemia in Malta
Author(s) -
Cauchi M. N.
Publication year - 1970
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1970.tb01422.x
Subject(s) - incidence (geometry) , glucose 6 phosphate dehydrogenase deficiency , enzyme deficiency , glucose 6 phosphate dehydrogenase , medicine , dehydrogenase , demography , endocrinology , enzyme , biology , biochemistry , physics , sociology , optics
S ummary . A survey of G6PD deficiency in Malta including 1145 males and 369 females has shown that 2.7% of the males and 1.9% of the females have enzyme deficiency. More than 60% of the enzyme‐deficient males but none of the females had decolorization times between 90 min and 24 hr. Using quantitative estimation of Hb A 2 as a measure of β‐thalassaemia, an incidence of 3.4–3.6% was found. A raised Hb F was found in 2.3% of cases. The incidence of G6PD deficiency and thalassaemia does not seem to be correlated with intermarriage.