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Blood Volume Changes in Splenomegaly
Author(s) -
Donaldson G. W. K.,
McArthur Marjory,
Macpherson A. I. S.,
Richmond J.
Publication year - 1970
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1970.tb01417.x
Subject(s) - splenectomy , plasma volume , medicine , blood volume , spleen , red cell , immunology , pathology
S ummary . Blood volume changes have been measured in 65 patients with splenomegaly due to a miscellany of causes. The red‐cell mass is often normal despite the fact that anaemia is present, and the anaemia is in part due to sequestration of red cells in a splenic pool and haemodilution of the red cells in an expanded plasma volume. Both factors may be relieved by splenectomy although the ultimate prognosis is dependent on the primary disease present.