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The Correlation between IgM Anti‐D and ‘Saline Agglutination’ of D‐positive Cells by Anti‐D Sera
Author(s) -
Hopkins D. F.
Publication year - 1969
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1969.tb01411.x
Subject(s) - titer , agglutination (biology) , saline , antibody , microbiology and biotechnology , immunology , chemistry , medicine , biology
S ummary . Sixty‐five sera which showed anti‐D activity were examined. A saline agglutinating anti‐D titre of 1, possibly of 2, does not necessarily imply that the serum contains IgM anti‐D, for this agglutination is sometimes due to IgG anti‐D in the presence of a sufficient concentration of other protein in the serum. A saline anti‐D titre of 4 or higher denotes IgM anti‐D.