Premium
In‐Vitro Lysis of AET‐Treated Normal Red Cells (PNH‐like Cells) by Normal and Cirrhotic Sera
Author(s) -
Sirchia G.,
Ferrone S.,
Mercuriali F.
Publication year - 1969
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1969.tb01369.x
Subject(s) - haemolysis , in vitro , titer , lysis , hemolysis , chemistry , microbiology and biotechnology , immunology , medicine , endocrinology , biology , biochemistry , antibody
S ummary . The total complement (C′) titre, the concentration of the third component of C (C′ 3 ) and the haemolytic activity against AET‐treated cells (PNH‐like cells) of normal and cirrhotic sera have been investigated. Serum haemolytic activity has been judged by the amount of haemolysis obtained in two in‐vitro tests, the acidified‐serum test and the sugar‐haemolysis test. A significant correlation has been found between total C’ titre and C′ 3 concentration of cirrhotic sera and the serum haemolytic activity against AET cells in the sugar‐haemolysis test.