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The Free Globin in Human Erythrocytes. I
Author(s) -
Winterhalter Kaspar H.,
Heywood J. David,
Huehns Ernst R.,
Finch Clement A.
Publication year - 1969
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1969.tb00434.x
Subject(s) - globin , alpha globulin , biology , chemistry , biochemistry , microbiology and biotechnology , hemoglobin , gene
Summary: A method of measuring free globin has been described. Human erythrocytes are shown to contain free globin and levels have been established for a group of haematologically normal individuals. Storage experiments indicate the importance of performing the free globin assay on fresh blood. Evidence is presented that this free globin is probably a mixture of α‐β apoprotein and intermediate α 2 ‐β 2 tetramers partially saturated with haem.