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The Measurement of Iron Clearance from the Skin
Author(s) -
Beamish M. R.,
Jacobs A.
Publication year - 1968
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1968.tb01534.x
Subject(s) - clearance , transferrin , blood stream , iron deficiency , medicine , half life , chemistry , physiology , anemia , urology , pharmacokinetics
Iron clearance from the skin was measured in 10 normal subjects and two patients with iron‐deficiency anaemia. Some of the iron injected into the skin is probably bound to transferrin in the interstitial fluid whilst the remainder is rapidly removed into the blood stream. Approximately two‐thirds of the bound iron is cleared with a half‐life of about 1 day, the remainder disappearing slowly with a half‐life of about 60 days.