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Red Cell Fatty Acids in Polycythaemia Vera
Author(s) -
Dhopeshwarkar G. A.,
Sukhatankar Usha N.
Publication year - 1968
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1968.tb01471.x
Subject(s) - arachidonic acid , chemistry , stearic acid , linoleic acid , phospholipid , red cell , oleic acid , polycythaemia , palmitic acid , triglyceride , fatty acid , biochemistry , cholesterol , medicine , organic chemistry , membrane , enzyme
S ummary Total lipids of red cells as well as plasma from polycythaemia Vera patients and normal subjects were fractionated and the fatty acid composition was analysed by gas‐liquid chromatography. The following statistically significant differences were found in the percent fatty acid levels. Red cell . Linoleic acid level of total lipids was decreased in polycythaemia whereas oleic acid level of phospholipid fractions was increased. Stearic acid level of cholesterol ester fraction was increased in polycythaemia whereas that of triglyceride fraction was decreased. Significantly low levels of arachidonic acid associated with cholesterol ester fraction were noted in polycythaemia patients. Plasma . Palmitic acid associated with total lipids and oleic acid levels of phospholipid fractions were higher in polycythaemia. Stearic acid associated with phosphatidyl ethanolamine was found to be decreased in polycythaemia. Similarly arachidonic acid associated with total lipids as well as sphingomyelin was decreased in polycythaemia. A wide difference between the lipids of the red cell and the surrounding plasma was observed.