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Lysis of P.N.H. Cells in Solutions of Low Ionic Strength
Author(s) -
Stratton F.,
Evans D. I. K.
Publication year - 1967
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1967.tb08857.x
Subject(s) - ionic strength , chemistry , albumin , sucrose , lysis , chromatography , ionic bonding , biochemistry , ion , aqueous solution , organic chemistry
SUMMARY A test to detect P.N.H. red cells when exposed to fresh serum in a sucrose‐veronal‐albumin buffer solution of low ionic strength, pH 7.6, is described. The serological findings suggest that the basis of the test is another example of the peculiar sensitivity of P.N.H. cells to complement in the presence of antibody.