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A Study of the Coagulant Properties of Malayan Pit‐Viper Venom
Author(s) -
Chan K. E.,
Rizza C. R.,
Henderson Marie P.
Publication year - 1965
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1965.tb00113.x
Subject(s) - viper , viper venoms , venom , medicine , coagulation , fibrinogen , antivenom , snake venom , biology , fishery
T he commonest cause of snake‐bite in Northern Malaya is the Malayan pit‐viper ( Ancistrodon rhodostoma ), more than 300 cases being recorded each year. In a study carried out by Reid, Thean, Chan and Baharom (1963), 39 per cent of the victims suffered systemic poisoning, the outstanding feature of which was a prolonged defect of blood coagulation due to complete or partial disappearance of fibrinogen from the blood (Reid, Chan and Thean, 1963). This paper describes in vitro experiments carried out to learn more about the action of the Malayan pit‐viper venom on the blood coagulation process and on the blood coagulation factors.