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Sézary syndrome associated with granulomatous lesions during treatment with bexarotene
Author(s) -
RuizdeCasas A.,
CarrizosaEsquivel A.,
HerreraSaval A.,
J. RiosMartín J.,
Camacho F.
Publication year - 2006
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.2005.07034.x
Subject(s) - medicine , bexarotene , dermatology , library science , family medicine , computer science , biology , biochemistry , nuclear receptor , transcription factor , gene
Summary Sézary syndrome (SS) is a leukaemic variant of cutaneous T‐cell lymphoma (CTCL). We report a patient with SS who developed granulomatous lesions. These lesions broke out during treatment with bexarotene when the disease had appeared to stabilize. After a partial clinical remission the disease showed rapid progression and finally led to the patient's death. This contradicts the initial assessment, which considered the granulomatous inflammation as a good prognostic factor in CTCL.
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