Premium
Delayed hypersensitivity reactions to corticosteroids applied to mucous membranes
Author(s) -
BIRCHER A.J.,
PELLONI F.,
MESSMER S.LANGAUER,
MÜLLER D.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1996.tb01169.x
Subject(s) - medicine , mucous membrane , dermatology , delayed hypersensitivity , corticosteroid , membrane , immunology , surgery , chemistry , biochemistry , antigen
Summary Despite the widespread use of corticosteroids on the mucous membranes of the nose, eye and bronchial tree, mucosal contact sensitivity has apparently been uncommon. However, since the introductinn of now corticosteroids such us tixocortol pivalate and budosonide, mucosal conlact sensitivity, particularly that affecting the nasal mucosa, has increasingly been reported. Contact allergy on other mucosal surfaces and in the bronchial tree is very rare. We report three women who had contact allergy to tixocortol pivalate or budesonide in nasal sprays, and one woman who had an allergic contact stomatitis from tixocortol pivalate in oral lozenges.