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Topical vitamin D 3 (tacalcitol) for steroid‐resistant prurigo
Author(s) -
KATAYAMA I.,
MIYAZAKI Y.,
NISHIKA K.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1996.tb01153.x
Subject(s) - prurigo nodularis , medicine , prurigo , dermatology , atopic dermatitis , topical steroid , regimen , surgery
Summary A topical vitamin D 3 , ointment (tacalcitol) was prescribed for patients with long‐histing pruriginous lesions (four with prurigo nodularis und seven with subacuLe prurigo, four of whom had atopic dermatitis). Seven of 11 cases had not responded to a topical steroid ointment and even to occlusive application of the ointment. Nine of 11 cases showed a significant clinical response to this new regimen within 4 weeks. Epidermal FceR1(+) dendritic cells were increased in number in prurigo nodularis and reduced to normal level after the therapy. Topical vitamin D 3 ointment might be an alternative therapy ibr steroid‐resistant prurigo.