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Bacillary angiomatosis in HIV‐infected patients: report of three cases with different clinical courses and identification of Rochalimaea quintana as the aetiological agent
Author(s) -
BACHELEZ H.,
OKSENHENDLER E.,
LEBBÉ C.,
DAUGA C.,
PINQUIER L.,
MAINGUENE C.,
CLAUVEL J.P.,
GRIMONT P.A.D.,
MOREL P.,
DUBERTRET L.,
ARLET G.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb06938.x
Subject(s) - bacillary angiomatosis , angiomatosis , etiology , polymerase chain reaction , aids related opportunistic infections , restriction fragment length polymorphism , biology , virology , medicine , pathology , human immunodeficiency virus (hiv) , immunology , viral disease , sida , bartonella henselae , genetics , serology , gene , antibody
Summary Three cases of cutaneous bacillary angiomatosis in HIV‐infected patients are reportcd. They differed proloundly with respeet to the extent of the lesions and the clinical course. In two cases, Rochtilinuiea quintana was identitied by direct scqucncing of the DNA ampliflcd with the polymerase chaiti reaction (PCR). whereas an easy, rapid method hased on the restriction length of polymorphisin analysis of PCR products (PCR‐RFLP) was used in the third case. This report illustrates the varialions in clinical presentations and evolutivc protiles in patients with baciltary angiomatosis, and contirms the causal role of R. quintana in this disease.