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Peripheral T‐cell lymphoma involving subcutaneous tissue
Author(s) -
CHO KH.,
OH JK.,
KIM CW.,
HEO DS.,
KIM ST.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb05030.x
Subject(s) - lymphoma , pathology , medicine , peripheral t cell lymphoma , peripheral , subcutaneous tissue , biopsy , virus , skin biopsy , epstein–barr virus , t cell , immunology , immune system
Summary The peripheral T‐cell lymphomas, presumably derived from various immunocompetent peripheral T‐cell system components, form a heterogeneous group of non‐Hodgkin's lymphomas. We describe two patients with peripheral T‐cell lymphoma primarily involving subcutaneous tissue. They presented with multiple subcutaneous nodules. Skin biopsy specimens in both patients demonstrated a lobular subcutaneous infiltrate. The infiltrate consisted of small and medium‐sized atypical lymphoid cells. Both patients had a protracted clinical course before they were diagnosed as having malignant lymphoma. We detected latent Epstein‐Barr virus infection in the skin lesions of case 2. Latent Epstein‐Barr virus infection might be related to the development of this variant of peripheral T‐cell lymphoma.