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Protracted cutaneous disorders in association with low CD4 + lymphocyte counts
Author(s) -
KURWA H.A.,
MARKS R.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb02717.x
Subject(s) - immunosuppression , lymphocyte , medicine , immunology , immunodeficiency , t lymphocyte , immunopathology , human immunodeficiency virus (hiv) , disease , pathology , immune system
Summary We report two patients with skin disorders usually associated with severe immunosuppression, who had low CD4 + lymphocyte counts but normal immunoglobulin levels. The patients were HIV negative, and had CD4 + lymphocyte counts just above 300/mm 3 , but they presented with cutaneous manifestations of profound immunodeficiency. Idiopathic CD4 + lymphocyte deficiency is a recently described syndrome which may present with dermatological disease. We discuss the symptom complex of our patients in relationship to the diagnosis of idiopathic CD4 + lymphocyte deficiency.