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Remission of severe epidermolysis bullosa acquisita induced by extracorporeal photochemotherapy
Author(s) -
MILLER J.L.,
STRICKLIN G.P.,
FINE J.D.,
KING L.E.,
ARZUBIAGA M. DEL CARMEN,
ELLIS D.L.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb02680.x
Subject(s) - epidermolysis bullosa acquisita , medicine , refractory (planetary science) , dermatology , epidermolysis bullosa , sepsis , surgery , immunology , autoantibody , physics , astrobiology , antibody
Summary We report a patient with severe epidermolysis bullosa acquisita (EBA) whose disease was refractory to conventional treatments. New bullae continued to develop over greater than 50% of his body surface area despite therapy. His course was complicated by hyperglyeaemia, sepsis, hypoxia caused by pulmonary Aspergillus infection and an idiopathic cardiomyopathy. His EBA resolved after treatment with extracorporeal photochemotherapy (ECP). Hence, ECP may be effective in the treatment of severe EBA which has failed to respond to standard treatment regimens.