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Successful treatment of epidermolysis bullosa acquisita using intravenous immunoglobulins
Author(s) -
MOHR C.,
SUNDERKÖTTER C.,
HILDEBRAND A.,
BIEL K.,
RÜTTER A.,
RÜTTER G.H.,
LUGER T.A.,
KOLDE G.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb00735.x
Subject(s) - epidermolysis bullosa acquisita , dapsone , medicine , intravenous immunoglobulins , dermatology , azathioprine , prednisone , antibody , epidermolysis bullosa , pathology , surgery , immunology , bullous pemphigoid , disease
Summary We report a 55‐year‐old man with severe inflammatory epidermolysis bullosa acquisita. The skin lesions did not respond to various immunosuppressive treatments. The combined administration of prednisone, azathioprine, dapsone and colchicine resulted only in a transient and incomplete resolution of the lesions. The bullae and increased skin fragility were successfully controlled by the addition of high‐dose intravenous immunoglobulin therapy.