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Successful treatment of hydroxyethyl starch‐induced pruritus with topical capsaicin
Author(s) -
SZEIMIES R.M.,
STOLZ W.,
WLOTZKE U.,
KORTING H.C.,
LANDTHALER M.
Publication year - 1994
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1994.tb08529.x
Subject(s) - capsaicin , antipruritic , medicine , hydroxyethyl starch , dermatology , anesthesia , starch , pharmacology , chemistry , food science , receptor
Summary We report a case of recalcitrant pruritus after infusion therapy with hydroxyethyl starch (HES) for sudden deafness. The diagnosis was confirmed by detection of typical HES storage vacuoles within dermal macrophages and perineural cells. Treatment with antihistamines and antipruritic agents, UVB irradiation, and neuroleptic drugs, was ineffective. Topical capsaicin (0.05%) twice daily produced excellent symptomatic relief, without side‐effects.