Premium
Photoallergic contact dermatitis to oxybenzone
Author(s) -
COLLINS P.,
FERGUSON J.
Publication year - 1994
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1994.tb08469.x
Subject(s) - dermatology , medicine , patch testing , photodermatosis , contact dermatitis , hair dyes , allergic contact dermatitis , sunscreening agents , contact allergy , sun exposure , allergy , chemistry , immunology , dna , biochemistry , organic chemistry , xeroderma pigmentosum , cancer , dyeing , skin cancer , dna damage
Summary A 21‐year‐old woman developed an erythematous papulovesicular eruption of photo‐exposed sites, following the use of an oxybenzone‐containing sunscreen. Patch testing, photopatch testing, phototesting, and histology produced findings strongly suggestive of oxybenzone photoallergy. Photopatch testing with a monochromator source showed abnormal UVA responses, with evidence of immediate urticaria, and delayed‐onset dermatitis. Sun‐barrier use is associated with a risk of the development of contact or photocontact allergic reactions. The benzophenones are frequently used in high‐protection factor sun‐barrier preparations, and appear to have a particular ability to induce such responses.