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Relevance of broad‐spectrum and fungicidal activity of antifungals in the treatment of dermatomycoses
Author(s) -
CLAYTON Y.M.
Publication year - 1994
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1994.tb06084.x
Subject(s) - broad spectrum , fungicide , dermatology , medicine , pharmacology , biology , chemistry , botany , combinatorial chemistry
Summary The in vitro fungistatic and fungicidal activities of terbinafine, amorolfine and itraconazole against dermatophytes were compared. All three compounds showed very good activity against all dermatophyte species tested, but only terbinafine and amorolfine exhibited primary fungicidal activity. These two compounds were also active in vitro against other filamentous fungi which cause onychomycoses, such as Scytalidium and Scopulariopsis species.