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One‐week therapy with oral terbinafine in cases of tinea cruris/corporis
Author(s) -
FARAG A.,
TAHA M.,
HALIM S.
Publication year - 1994
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1994.tb04983.x
Subject(s) - terbinafine , tinea capitis , medicine , dermatology , dermatophyte , itraconazole , antifungal
Summary The use of oral terbinafine in the treatment of superficial dermatophyte infections has been extensively studied, using different treatment regimens. To evaluate the efficacy of short‐term therapy with oral terbinafine in cases of tinea cruris/corporis. 22 patients (21 male and one female) with mycologically proven tinea cruris/corporis, were included in the present study. Each patient received one tablet of terbinafine 250 mg daily for 1 week. Patients were followed‐up for 6 weeks after completion of treatment. Clinical and mycological assessments were performed at the end of treatment, and at the end of the follow‐up period. The mean sum of scores of signs and symptoms in all patients decreased significantly from 12‐36 before treatment to 0 at the end of the follow‐up period, and mycological investigations were negative in all patients at the end of the follow‐up period. Our results show that 1‐week therapy with oral terbinafine is highly effective in the treatment of tinea cruris/corporis.