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The effects of ultraviolet light irradiation on viral infections
Author(s) -
NORVAL M.,
ELGHORR A.,
GARSSEN J.,
LOVEREN H.
Publication year - 1994
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1994.tb03404.x
Subject(s) - ultraviolet irradiation , irradiation , ultraviolet light , ultraviolet , medicine , chemistry , materials science , photochemistry , physics , optoelectronics , nuclear physics
Summary Exposure to ultraviolet radiation is associated with the development of cutaneous carcinomas, and with suppression of immune responses to a variety of antigens, including those of fungal, bacterial and parasitic origin, and contact sensitizers. UV irradiation also influences viral infections. It can affect viral mutation, the photolocalization of viral exanthems, viral oncogenesis, activation of viral genomes, and the suppression of immune responses to viruses. The evidence for, and mechanisms involved in, each of these categories is presented, and the effect of UV radiation on the virus‐host interaction, particularly during persistent infections, is discussed.