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A comparison of narrow band phototherapy (TL‐01) and photochemotherapy (PUVA) in the management of polymorphic light eruption
Author(s) -
BILSLAND D.,
GEORGE S.A.,
GIBBS N.K.,
AITCHISON T.,
JOHNSON B.E.,
FERGUSON J.
Publication year - 1993
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1993.tb03337.x
Subject(s) - dermatology , medicine , methoxsalen , puva therapy , placebo , skin type , psoriasis , pathology , alternative medicine
Summary Twenty‐five patients suffering from severe polymorphic light eruption (PLE) were randomized to either photochemotherapy (PUVA) or narrow‐band phototherapy (TL‐Ol UVB) treatment in early spring; patients receiving UVB were given placebo tablets to achieve a matching therapy procedure. During the 4 months following treatment, patient exposure to solar UVB was monitored with polysulphone badges. PLE occurrence, severity, and restriction of outdoor activity were recorded, using weekly diary‐sheets. Analysis of covariance on this data, using the logarithm of UVB exposure as the explanatory variable, showed no significant differences between the treatments. TL–01 UVB is an effective alternative to PUVA in the management of PLE.