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Serious childhood angiomas: unsuccessful alpha‐2b interferon treatment. A report of four cases
Author(s) -
TEILLACHAMEL D.,
PROST Y.,
BODEMER C.,
ANDRY P.,
ENJOLRAS O.,
SEBAG G.,
BRUNELLE F.,
HUBERT P.,
NIHOULFEKETE C.
Publication year - 1993
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1993.tb03181.x
Subject(s) - alpha interferon , medicine , alpha (finance) , pediatrics , dermatology , interferon , immunology , surgery , construct validity , patient satisfaction
Summary Over a 4‐year period, we managed four children with alarming haemangiomas (two cases of Kasabach‐Merritt syndrome and two life‐threatening haemangiomas). Systemic steroid therapy was ineffective. Other treatments (radiotherapy, anti‐platelet drugs) were also ineffective in the Kasabach‐Merritt patients. On the basis of recent reports on the effects of interferon on endothelial cells, we used alpha‐2 interferon therapy, but obtained no response.