Premium
High frequency, high resolution B‐scan ultrasound in the assessment of skin tumours
Author(s) -
HARLAND C.C.,
BAMBER J.C.,
GUSTERSON B.A.,
MORTIMER P.S.
Publication year - 1993
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1993.tb00229.x
Subject(s) - echogenicity , ultrasound , medicine , histology , skin thickness , nuclear medicine , pathology , radiology , biopsy , biomedical engineering
Summary Sixteen skin tumours and one BCG vaccination granuloma were examined by 20‐MHz B‐scan ultrasound. Images were compared with closely matched histological sections of excised lesions. The correlation between histology and ultrasound was excellent for maximum tumour depth measurements (r=0.96, P <0.0001), but less good for maximum width (r=0.84, P <0.0001) because of the elastic contraction of tissue at excision. Architectural detail of lesions on histological sections corresponded well with that on ultrasound images. There was a good correlation for heterogeneity (collagen distribution vs. echo pattern (r=0.86, P <0.0001)), and between collagen content and echogenicity of lesions (r=0.69, P <0.003), Strong correlations were also obtained for echogenicity vs. spacing of collagen bundles (r=−0.65, P <0.005), echogenicity vs. collagen bundle size (r=0.58, P <0.02), and echogenicity vs. cellularity (r=−0.68, P <0.003). Results for dermatofibroma were atypical, due to paradoxical low internal echogenicity and increased echo absorption. B‐scanning is a reliable non‐invasive method for assessing tumour dimensions, and has potential for the study of tumour characteristics for diagnostic purposes.