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A child with xeroderma pigmentosum and bone marrow failure
Author(s) -
SALOB S.P.,
WEBB D.K.H.,
ATHERTON D.J.
Publication year - 1992
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1992.tb00681.x
Subject(s) - xeroderma pigmentosum , bone marrow , medicine , bone marrow transplantation , hypoplasia , bone marrow failure , pathology , dermatology , cancer research , stem cell , dna repair , biology , genetics , dna , surgery , haematopoiesis
Summary The case of a child with both xeroderma pigmentosum and bone marrow failure is reported. It is suggested that this is not a chance association, and that the bone marrow hypoplasia may reflect an increased susceptibility of this patient's haemopoietic stem cells to non‐UV mutagens.