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The prognosis of patients with lymphomatoid papulosis associated with malignant lymphomas
Author(s) -
BELJAARDS R.C.,
WILLEMZE R.
Publication year - 1992
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1992.tb00106.x
Subject(s) - lymphomatoid papulosis , mycosis fungoides , medicine , cd30 , lymphoma , malignant lymphoma , dermatology , disease , large cell , pathology , cancer , adenocarcinoma
Summary Lymphomatoid papulosis (LyP) is a disorder which generally runs a benign course, but can sometimes be associated with a malignant lymphoma. Information about the prognosis of these LyP‐associated lymphomas is, however, fragmentary. In this study, the clinical data of 50 LyP‐associated malignant lymphomas, including 11 patients of our own group and 39 reported in the literature, are evaluated. Three main groups of LyP‐associated malignant lymphomas could be distinguished: cases associated with mycosis fungoides (19/50 cases). Hodgkin's disease (12/50 cases) and (CD30 + ) large‐cell lymphomas (16/50). The results of this study demonstrate that patients with mycosis fungoides. Hodgkin's disease, and (CD30 + ) large‐cell lymphomas limited to the skin have a favourable prognosis. However, the prognosis of patients developing a systemic (CD30 + ) large‐cell lymphoma proved generally poor. The results of this study also indicate that the risk of an individual LyP patient developing systemic lymphoma is less than 5%.