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Necrobiosis lipoidica: treatment with systemic corticosteroids
Author(s) -
PETZELBAUER P.,
WOLFF K.,
TAPPEINER G.
Publication year - 1992
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1992.tb00097.x
Subject(s) - necrobiosis lipoidica , medicine , dermatology , disease , surgery , systemic disease , diabetes mellitus , endocrinology
Summary In an attempt to find an effective therapy for necrobiosis lipoidica, we have treated six patients with this disease with a 5‐week course of systemic corticosteroids. This treatment resulted in complete cessation of disease activity in all patients and no recurrence in a mean follow‐up period of 7 months; however, restitution of atrophic skin lesions could not be achieved. The therapy was well tolerated and did not pose problems, even in diabetic patients. These results strongly suggest that short‐course therapy of necrobiosis lipoidica with corticosteroids is of lasting benefit to these patients and should probably be considered early in the course of their skin disease.