Premium
The epidermal basement membrane in basal cell carcinoma: an immunohistochemical study
Author(s) -
MARKEY A. C.,
TIDMAN M. J.,
CHURCHILL L. J.,
APLIN J. D.,
LEIGH I. M.,
PURKIS P.,
MACDONALD D. M.
Publication year - 1991
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1991.tb06033.x
Subject(s) - immunohistochemistry , basement membrane , pathology , basal cell carcinoma , antibody , antigen , basal (medicine) , biology , carcinoma , basal cell , medicine , immunology , endocrinology , insulin
Summary An immunohistochemical study of basal cell carcinomas of varying histological type, using a panel of antibodies to constituents of the epidermal basement membrane, showed marked deficiencies in the expression of the antigens identified by the antibodies LH7.2.GB3 and G71. There was no correlation between loss of immunoreactivity to these antibodies and the histological features of the tumour.