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Increased tryptase levels in suction‐blister fluid from patients with urticaria
Author(s) -
DELEURAN B.,
KRISTENSEN METTE,
LARSEN C. GRøNHøJ,
MATSSON P.,
ENANDER INGRID,
ANDERSSON ANNSOFIE,
THESTRUPPEDERSEN K.
Publication year - 1991
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1991.tb06031.x
Subject(s) - medicine , university hospital , dermatology , library science , art history , family medicine , history , computer science
Summary The levels of tryptase in the suction‐blister fluid from patients with chronic urticaria, urticaria pigmentosa, cholinergic urticaria, urticarial dermographism, prurigo of unknown origin, eczema, psoriasis, atopic dermatitis, and from healthy controls were studied. The blister fluid from controls contained up to 15 μg/l of tryptase, whereas that from patients with active urticaria contained > 50 μg/l. This study demonstrates that patients with urticaria have mast cells that readily release tryptase in both the lesional and non‐lesional areas of skin.