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Epidermodysplasia verruciformis‐associated papillomavirus infection complicating human immunodeficiency virus disease
Author(s) -
BERGER T.G.,
SAWCHUK W.S.,
LEONARDI C.,
LANGENBERG ANDRIA,
TAPPERO J.,
LEBOIT P.E.
Publication year - 1991
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1991.tb03286.x
Subject(s) - epidermodysplasia verruciformis , virology , human immunodeficiency virus (hiv) , human papillomavirus , viral disease , medicine , virus , disease , pathology
Summary Three males infected with the human immunodeficiency virus(HIV) were noted to have extensive flat warts of the face and/or body. In two there were also pityriasis versicolor‐like lesions. Biopsies showed foamy, basophilic, distended cytoplasm in granular layer keratinocytes, characteristic of the human papillomavirus types seen in epidermodysplasia verruciformis. DNA hybridzation techniques demonstrated the presence of HPV‐type 8 in one patient and HPV 5 and 8 in another. Patients with immune suppression due to HIV infection may demonstrate the clinical features of epidermodysplasia verruciformis with the same potentially oncogenic HPV types.