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Intraepidermal leakage of plasma proteins after tape stripping of normal skin and uninvolved psoriatic skin
Author(s) -
VERSCHOORE M.,
KOWALEWSKI C.,
CHORZHLSKA M.JARZABEK,
BERNARD B.A.,
DARMON Y.M.
Publication year - 1990
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1990.tb08288.x
Subject(s) - psoriasis , epidermis (zoology) , peripheral blood mononuclear cell , fibrinogen , fibronectin , medicine , chemistry , pathology , dermatology , cell , anatomy , in vitro , biochemistry
SUMMARY Following tape stripping of normal skin and uninvolved psoriatic skin, there was an early leakage of plasma proteins such as fibrinogen, fibronectin and immunoglobulins. This was accompanied by migration of mononuclear and polymorphonuclear cells into the epidermis. Both events appeared earlier, were more pronounced and lasted longer in psoriatic subjects than in controls.