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Granulomatous cheilitis and Crohn's disease
Author(s) -
KANO Y.,
SHIOHARA T.,
YAGITA A.,
NAGASHIMA M.
Publication year - 1990
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1990.tb06303.x
Subject(s) - dermatology , medicine , family medicine , library science , computer science
SUMMARY A case of granulomatous cheilitis is reported in whom investigations showed intestinal involvement compatible with Crohn's disease, although the patient had no gastrointestinal symptoms. Granulomatous cheilitis (GC) is an uncommon disorder that is characterized by persistent swelling of the lips and a granulomatous histology. Since the report of a case of GC that occurred several years before intestinal lesions appeared, 1 GC has been recognized to be an early manifestation of Crohn's disease. However, to our knowledge only four cases have been reported that initially presented with GC and then developed Crohn's disease. 1–4 Whether GC represents an early manifestation of Crohn's disease or a distinct clinico‐pathological entity remains controversial. 5 We describe a patient with GC who had intestinal lesions compatible with the diagnosis of Crohn's disease, although she had no gastrointestinal symptoms.