Premium
Isotretinoin, creatine kinase and exercise
Author(s) -
Tillman D.M.,
White S.I.,
Aitchison T.C.
Publication year - 1990
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1990.tb04418.x
Subject(s) - isotretinoin , creatine kinase , medicine , physical therapy , dermatology , acne
acne. The response was graded o (normal) to 15 (most disabled). Sixty-six newly referred patients with acne, 40 male, aged 13-53 (median 21-5) years, completed the questionnaire without supervision; acne severity was graded clinically by comparison with photographic scales. Both were repeated at follow-up visits. At presentation the range of acne severity (cumulative: face + chest + back) was from o-1 to 10-5 (mean 3-2). The range of disability score was from 2 to 14 (mean 6-5). Overall, there was no significant correlation between acne severity and disability score, although one question strongly correlated with the severity of acne on the back. Twenty-three patients did not attend after the first visit. Twenty-two patients (15 male) were treated with antibiotics and were followed for 1-7 (mean 38) months. During this period the mean cumulative acne severity remained at i -8, but the mean disability score fell from 52 to 18. Sixteen patients (nine male) were treated with isotretinoin and followed for a period of 2-9 (mean 5) months. During this period the mean cumulative acne severity fell from 2-0 to 0-4 and the mean disability score fell from 5-2 to 3-7. One patient was identified as dysmorphophobic on the basis of a mean acne severity of o and a disability score of 12. This short questionnaire adds a patient-orientated dimension to the routine assessment of acne severity and may identify patients with higher levels of disability.