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A 4% erythromycin and zinc combination (Zineryt®) versus 2% erythromycin (Eryderm®) in acne vulgaris: a randomized, double‐blind comparative study
Author(s) -
HABBEMA L.,
KOOPMANS B.,
MENKE H.E.,
DOORNWEERD S.,
BOULLE K.
Publication year - 1989
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1989.tb15518.x
Subject(s) - lotion , acne , erythromycin , medicine , dermatology , randomized controlled trial , antibiotics , surgery , pharmacology , chemistry , biochemistry
SUMMARY A double‐blind, randomized multi‐centre study was performed to evaluate the efficacy of a 4% erythromycin and zinc combination (Zineryt®) versus 2% erythromycin (Eryderm®). One‐hundred and twenty‐two patients suffering from acne vulgaris were treated with either Zineryt® lotion or 2% erythromycin lotion. Acne grading and lesion counts for comedones, papules, pustules, nodules and macules were performed at each visit at 0, 1, 2, 4, 8 and 12 weeks. Treatment with Zineryt® lotion was found to be more effective than with 2% erythromycin as regards the reduction in number of the acne lesions and the severity grade of the acne.