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Thyroid disease in pustulosis palmoplantaris
Author(s) -
AGNER T.,
SINDRUP J.H.,
HøIERMADSEN MIMI,
HEGEDÜS L.
Publication year - 1989
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1989.tb15516.x
Subject(s) - medicine , pustulosis , thyroid , thyroid disease , incidence (geometry) , autoantibody , anti thyroid autoantibodies , hormone , graves' disease , disease , gastroenterology , endocrinology , immunology , antibody , physics , arthritis , optics , synovitis
SUMMARY An increased frequency of thyroid autoantibodies has been reported in patients with palmar and plantar pustulosis (PPP). This study was undertaken to determine the frequency and type of thyroid disease in 32 patients with this disease compared with a control group. Thyroid disease was demonstrated in 53% of the patients with PPP as compared to 16% in the matched control group. Fourteen patients with PPP had an enlarged thyroid and in six there were thyroid autoantibodies. There appears to be an increased incidence of goiter and thyroid autoantibodies in PPP with a decrease in the level of the thyroid hormones.