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Large cell anaplastic lymphoma of the skin
Author(s) -
FELLER A.C.,
STERRY W.
Publication year - 1989
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1989.tb08191.x
Subject(s) - mycosis fungoides , anaplastic large cell lymphoma , cd30 , immunophenotyping , lymphoma , medicine , pathology , large cell , antigen , dermatology , immunology , cancer , adenocarcinoma
SUMMARY Large cell anaplastic lymphoma (LCAL) is a recently described entity recognized by its constant expression of the CD30 antigen and by its morphology. LCAL is classified as high grade malignant lymphoma. We report 10 patients with LCAL of the skin, three with primary LCAL and others in which it developed with cutaneous T‐cell lymphoma, mainly mycosis fungoides. The immunophenotype in all but one of these cases, was that of activated T cells.