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Dermatoses in five related female carriers of X‐linked chronic granulomatous disease
Author(s) -
GARIOCH JENNIFER J.,
SAMPSON J.R.,
SEYWRIGHT MORAG,
THOMSON J.
Publication year - 1989
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1989.tb01434.x
Subject(s) - chronic granulomatous disease , disease , medicine , genetic counseling , prenatal diagnosis , family history , immunology , dermatology , pathology , genetics , biology , pregnancy , fetus
SUMMARY Eight female members of a family with X‐linked chronic granulomatous disease were identified. Five were shown to be carriers of the disease gene. Each of these female carriers of the gene had a history of skin eruptions. The identification of the carrier state is important as genetic counselling should be offered and the prenatal diagnosis of this disorder is possible.