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UVA sunbeds: tanning, photoprotection, acute adverse effects and immunological changes
Author(s) -
RIVERS J.K.,
NORRIS P.G.,
MURPHY G.M.,
CHU A.C.,
MIDGLEY G.,
MORRIS J.,
MORRIS R.W.,
YOUNG A.R.,
HAWK J.L.M.
Publication year - 1989
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1989.tb01374.x
Subject(s) - erythema , dermatology , medicine , adverse effect , photoprotection , immunology , biology , botany , photosynthesis
SUMMARY The effects on 31 normal subjects following exposure to sunbeds containing UVA lamps with minimal UVB emission have been compared in a double‐blind study with the effects on nine control subjects of a similar exposure course three times weekly for 4 weeks to sunbeds emitting visible light. On previously untanned areas, all those subjects on active treatment developed a mild tan; in tanned areas they all developed a moderate tan, while all control subjects developed a minimal to mild tan. The mean protection factor against later UVB‐induced erythema was 3.2±0.3 after the active course and 1.6±0.2 among the controls. Significantlsy more frequent adverse cutaneous effects for active subjects were pruritus, erythema, freckling, burning sensation, dryness and polymorphic light eruption. Cutaneous Langerhans cell numbers, and blood CD3 + (pan T‐cell) and CD4 + (helper T‐cell) lymphocyte subsets were reduced in both active and control groups. CD8 + (cytotoxic/suppressor T‐cell) counts were significantly reduced in both groups. The changes found in both groups seem attributable to small amounts of UVB emission from both active and control lamps.