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Epidermolysis bullosa acquisita associated with vesicular cystitis
Author(s) -
LEE CHANG
Publication year - 1988
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1988.tb07109.x
Subject(s) - epidermolysis bullosa acquisita , lamina propria , medicine , pathology , autoantibody , cicatricial pemphigoid , urinary bladder , dermatology , mucous membrane , pemphigoid , epithelium , immunology , urology , bullous pemphigoid , antibody
SUMMARY A 55‐year‐old woman with epidermotysis bullosa acquisita (EBA) who had associated vesicular cystitis is described. The clinical, histological and immunohistological features of the skin and mucous membranes were in accordance with previous reports of this disease. The patient also had symptoms of cystitis, and a cystoscopic examination showed areas of erosions and vesicles in the wall of the urinary bladder, Histological and immunopathological studies of the urinary bladder demonstrated sub‐mucosal vesicles, and linear deposits of IgG and C 3 along the mucosal‐lamina propria junction. These bladder changes may be induced by the autoantibodies present in EBA.