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A comparative study of benzoyl peroxide and clindamycin phosphate for treating acne vulgaris
Author(s) -
SWINYER L.J.,
BAKER M.D.,
SWINYER THALIA A.,
MILLS O.H.
Publication year - 1988
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1988.tb03472.x
Subject(s) - salt lake , benzoyl peroxide , library science , acne , medicine , dermatology , chemistry , computer science , geology , organic chemistry , polymerization , polymer , paleontology , structural basin
SUMMARY A water based 5% benzoyl peroxide gel (Benzac® W5) was compared with topical 1% clindamycin phosphate solution (Cleocin T®) in the treatment of acne vulgaris using a randomized, investigator blind study design. Lesion counts were significantly reduced in both treatment groups over the 12‐week study period; however, the reduction of total lesions produced by benzoyl peroxide gel was significantly greater than that produced by clindamycin phosphate ( P < 0.05). Clindamycin phosphate had a milder effect on the skin surface in terms of peeling and drying than the benzoyl peroxide gel.