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Remarkable response of lipoid proteinosis to oral dimethyl sulphoxide
Author(s) -
WONG CHUKWAN,
LIN CHRANGSHI
Publication year - 1988
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1988.tb03260.x
Subject(s) - medicine , oral administration , dermatology , gastroenterology
SUMMARY We report the successful treatment of lipoid proteinosis in a 41‐year‐old man using oral dimethyl sulphoxide. The initial dosage was 40 mg/kg/day, which was then increased progressively to 60 mg/kg/day. After 3 years of treatment, the patient's skin lesions, hoarseness of voice and abnormal oesophageal function improved remarkably. No side‐effects were noted except for a garlic‐like smell on the patient's breath.