Premium
Recovery of cutaneous immune responsiveness after PUVA therapy
Author(s) -
WHITE S.I.,
FRIEDMANN P.S.,
MOSS C.,
SIMPSON J.M.
Publication year - 1988
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1988.tb02435.x
Subject(s) - puva therapy , medicine , dermatology , immune system , psoriasis , immunology
SUMMARY We studied sensitization to dinitrochlorobenzene (DNCB) in psoriatic patients before, during and 2,4, and 6 weeks after a course of photochemotherapy (PUVA). The inhibition of sensitivity observed during PUVA was completely reversed after 6 weeks. Thus the PUVA‐mediated inhibition of cutaneous immune responsiveness is of short duration. However, whether there are long‐term sequelae remains to be established.